UPDATE:

Anthony Brady was located deceased in a hotel on Sheridan Street around 4pm on Friday 14 August.

Detectives investigating the death of the 52-year-old Brisbane man in Cairns have charged a 32-year-old woman with manslaughter. 

EARLIER:

Police are seeking assistance from the community to locate a 52-year-old Brisbane man who was last seen in the Cairns area on Wednesday.

Anthony Brady (pictured) arrived in Cairns on Monday for business purposes and was due to return to Brisbane on Thursday afternoon.